Vectors for Human PRKAG3

Gene Information

  • Offical Gene Symbol PRKAG3
  • Species Human (Homo sapiens)
  • Offical Full Name protein kinase AMP-activated non-catalytic subunit gamma 3
  • Other Aliases AMPKG3; SMGMQTL
  • Other Desigations 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-3 subunit; AMPK gamma-3 chain; AMPK gamma3; AMPK subunit gamma-3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 53632
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PRKAG3(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKAG3 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PRKAG3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PRKAG3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PRKAG3 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PRKAG3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKAG3 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PRKAG3 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PRKAG3 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PRKAG3 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKAG3 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PRKAG3 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PRKAG3 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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