Vectors for Human ADAMTS18

Gene Information

  • Offical Gene Symbol ADAMTS18
  • Species Human (Homo sapiens)
  • Offical Full Name ADAM metallopeptidase with thrombospondin type 1 motif 18
  • Other Aliases ADAMTS21; KNO2; MMCAT
  • Other Desigations A disintegrin and metalloproteinase with thrombospondin motifs 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21; disintegrin and metalloprotease-like protein
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016]
  • NCBI Gene ID 170692
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ADAMTS18(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS18 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ADAMTS18 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ADAMTS18 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ADAMTS18 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ADAMTS18 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS18 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ADAMTS18 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ADAMTS18 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ADAMTS18 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADAMTS18 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ADAMTS18 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ADAMTS18 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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