Vectors for Zebrafish syngap1b

Gene Information

  • Offical Gene Symbol syngap1b
  • Species Zebrafish (Danio rerio)
  • Offical Full Name synaptic Ras GTPase activating protein 1b
  • Other Aliases si:dkey-246f6.1
  • Other Desigations ras/Rap GTPase-activating protein SynGAP1b; synaptic Ras GTPase activating protein 1b; syngap1
  • Gene Type protein-coding
  • 개요
    This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. In mammals, the N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. In humans, allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Morpholino knockdown of this gene in zebrafish results in neural cell death, developmental delay of mid- and hindbrain regions, seizure-like behavior, and disrupted motor behaviors. [provided by RefSeq, Nov 2016]
  • NCBI Gene ID 100151149
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Zebrafish syngap1b(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Zebrafish syngap1b expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Zebrafish syngap1b expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Zebrafish syngap1b expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Zebrafish syngap1b expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Zebrafish syngap1b expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189

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