Vectors for Mouse Scnn1b

Gene Information

  • Offical Gene Symbol Scnn1b
  • Species Mouse (Mus musculus)
  • Offical Full Name sodium channel, nonvoltage-gated 1 beta
  • Other Aliases -
  • Other Desigations amiloride-sensitive sodium channel subunit beta; ENaC beta; SCNEB; beta-ENaC; beta-NaCH; epithelial Na(+) channel subunit beta; nonvoltage-gated sodium channel 1 subunit beta
  • Gene Type protein-coding
  • 개요
    Enables WW domain binding activity and ligand-gated sodium channel activity. Contributes to sodium channel activity. Acts upstream of or within several processes, including cellular response to aldosterone; leukocyte activation involved in inflammatory response; and monovalent inorganic cation homeostasis. Located in external side of plasma membrane. Is integral component of membrane. Part of plasma membrane protein complex and sodium channel complex. Is expressed in several structures, including aorta; endocrine gland; genitourinary system; lung; and stomach. Used to study Liddle syndrome; autosomal recessive pseudohypoaldosteronism type 1; and cystic fibrosis. Human ortholog(s) of this gene implicated in Liddle syndrome; autosomal recessive pseudohypoaldosteronism type 1; bronchiectasis 1; and pseudohypoaldosteronism. Orthologous to human SCNN1B (sodium channel epithelial 1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 20277
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Scnn1b(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scnn1b expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Scnn1b expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Scnn1b expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Scnn1b expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Scnn1b expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scnn1b shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Scnn1b shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Scnn1b shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Scnn1b shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scnn1b CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Scnn1b CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Scnn1b CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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