Vectors for Mouse Scn8a

Gene Information

  • Offical Gene Symbol Scn8a
  • Species Mouse (Mus musculus)
  • Offical Full Name sodium channel, voltage-gated, type VIII, alpha
  • Other Aliases C630029C19Rik; NaCh6; Nav1.6; dmu; med; mnd-2; mnd2; nmf2; nmf335; nmf58; nur14; seal
  • Other Desigations sodium channel protein type 8 subunit alpha; ataxia 3; sodium channel protein type VIII subunit alpha; voltage-gated sodium channel alpha subunit; voltage-gated sodium channel subunit alpha Nav1.6
  • Gene Type protein-coding
  • 개요
    Predicted to enable sodium ion binding activity and voltage-gated sodium channel activity. Acts upstream of or within several processes, including adult walking behavior; muscle organ development; and sensory perception of sound. Located in several cellular components, including Z disc; neuronal cell body; and node of Ranvier. Part of sodium channel complex. Is expressed in several structures, including heart; metanephros; nervous system; and nucleus pulposus. Used to study early infantile epileptic encephalopathy and epilepsy. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and developmental and epileptic encephalopathy 13. Orthologous to human SCN8A (sodium voltage-gated channel alpha subunit 8). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 20273
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Scn8a(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scn8a expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Scn8a expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Scn8a expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Scn8a expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Scn8a expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scn8a shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Scn8a shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Scn8a shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Scn8a shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Scn8a CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Scn8a CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Scn8a CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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