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  3. Vectors for Mouse Nefl

Vectors for Mouse Nefl

Gene Information

  • Offical Gene Symbol Nefl
  • Species Mouse (Mus musculus)
  • Offical Full Name neurofilament, light polypeptide
  • Other Aliases CMT2E; NF-L; NF68; Nfl
  • Other Desigations neurofilament light polypeptide; 68 kDa neurofilament protein; neurofilament triplet L protein
  • Gene Type protein-coding
  • 개요
    Enables protein-macromolecule adaptor activity. A structural constituent of postsynaptic intermediate filament cytoskeleton. Involved in intermediate filament bundle assembly and synapse maturation. Acts upstream of or within several processes, including cytoskeleton organization; generation of neurons; and regulation of axon diameter. Located in several cellular components, including cholinergic synapse; intermediate filament cytoskeleton; and neuromuscular junction. Is active in Schaffer collateral - CA1 synapse and postsynaptic intermediate filament cytoskeleton. Is expressed in several structures, including alimentary system; central nervous system; eye; limb; and peripheral nervous system ganglion. Used to study Charcot-Marie-Tooth disease type 2E. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease (multiple); amyotrophic lateral sclerosis; and invasive ductal carcinoma. Orthologous to human NEFL (neurofilament light chain). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 18039
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Nefl(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nefl expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Nefl expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Nefl expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Nefl expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Nefl expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nefl shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Nefl shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Nefl shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Nefl shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Nefl CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Nefl CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Nefl CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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