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  3. Vectors for Mouse Mecp2

Vectors for Mouse Mecp2

Gene Information

  • Offical Gene Symbol Mecp2
  • Species Mouse (Mus musculus)
  • Offical Full Name methyl CpG binding protein 2
  • Other Aliases 1500041B07Rik; D630021H01Rik; Mbd5; WBP10
  • Other Desigations methyl-CpG-binding protein 2; meCp-2 protein
  • Gene Type protein-coding
  • 개요
    Enables several functions, including nucleic acid binding activity; promoter-specific chromatin binding activity; and transcription corepressor activity. Involved in several processes, including negative regulation of smooth muscle cell differentiation; negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; and positive regulation of histone H3-K9 trimethylation. Acts upstream of or within several processes, including glycerolipid metabolic process; nervous system development; and regulation of gene expression. Located in cytosol; heterochromatin; and nucleus. Is expressed in several structures, including alimentary system; early conceptus; nervous system; paraxial mesenchyme; and sensory organ. Used to study Rett syndrome. Human ortholog(s) of this gene implicated in Rett syndrome; X-linked intellectual disability-psychosis-macroorchidism syndrome; autistic disorder; severe congenital encephalopathy due to MECP2 mutation; and syndromic X-linked intellectual disability Lubs type. Orthologous to human MECP2 (methyl-CpG binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 17257
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | Ensembl |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Mouse Mecp2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mecp2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Mouse Mecp2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Mouse Mecp2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Mouse Mecp2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Mouse Mecp2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mecp2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Mouse Mecp2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Mouse Mecp2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Mouse Mecp2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mecp2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Mecp2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Mouse Mecp2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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