Vectors for Mouse Mdm4

Gene Information

  • Offical Gene Symbol Mdm4
  • Species Mouse (Mus musculus)
  • Offical Full Name transformed mouse 3T3 cell double minute 4
  • Other Aliases 4933417N07Rik; Mdmx
  • Other Desigations protein Mdm4; double minute 4 protein; mdm2-like p53-binding protein; p53-binding protein Mdm4; protein Mdmx
  • Gene Type protein-coding
  • 개요
    This gene encodes a protein that has been shown to negatively regulate the activity of the tumor suppressor protein p53. Homozygous knockout mice exhibit embryonic lethality as a result of p53-dependent apoptosis and cell cycle arrest. Amplification of this gene or overexpression of the encoded protein has been linked to a range of human cancers. A pseudogene has been identified on the X chromosome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]
  • NCBI Gene ID 17248
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Mdm4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mdm4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Mdm4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Mdm4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Mdm4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Mdm4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mdm4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Mdm4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Mdm4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Mdm4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mdm4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Mdm4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Mdm4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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