Vectors for Mouse Mcl1

Gene Information

  • Offical Gene Symbol Mcl1
  • Species Mouse (Mus musculus)
  • Offical Full Name myeloid cell leukemia sequence 1
  • Other Aliases Gm52627; Mcl-1
  • Other Desigations induced myeloid leukemia cell differentiation protein Mcl-1 homolog; bcl-2-related protein EAT/mcl1
  • Gene Type protein-coding
  • 개요
    Enables BH3 domain binding activity. Involved in extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of apoptotic process; and positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. Acts upstream of or within apoptotic mitochondrial changes and intrinsic apoptotic signaling pathway in response to DNA damage. Located in several cellular components, including cytosol; mitochondrial matrix; and nucleus. Is expressed in several structures, including alimentary system; blastocyst; brain; genitourinary system; and hemolymphoid system gland. Orthologous to human MCL1 (MCL1 apoptosis regulator, BCL2 family member). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 17210
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Mcl1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mcl1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Mcl1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Mcl1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Mcl1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Mcl1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mcl1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Mcl1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Mcl1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Mcl1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Mcl1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Mcl1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Mcl1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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