Vectors for Mouse Gli3

Gene Information

  • Offical Gene Symbol Gli3
  • Species Mouse (Mus musculus)
  • Offical Full Name GLI-Kruppel family member GLI3
  • Other Aliases Bph; GLI3-190; GLI3FL; Pdn; Xt; add
  • Other Desigations transcriptional activator GLI3; GLI3 form of 190 kDa; GLI3 full length protein; anterior digit pattern deformity; brachyphalangy; extra toes; polydactyly Nagoya; zinc finger protein GLI3
  • Gene Type protein-coding
  • 개요
    Enables DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including negative thymic T cell selection; regulation of alpha-beta T cell differentiation; and thymocyte apoptotic process. Acts upstream of or within several processes, including animal organ development; nervous system development; and positive regulation of cell differentiation. Located in axoneme and nuclear speck. Part of transcription repressor complex. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Used to study Greig cephalopolysyndactyly syndrome and Pallister-Hall syndrome. Human ortholog(s) of this gene implicated in Greig cephalopolysyndactyly syndrome; Pallister-Hall syndrome; anodontia; polydactyly; and syndactyly. Orthologous to human GLI3 (GLI family zinc finger 3). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 14634
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Gli3(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gli3 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Gli3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Gli3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Gli3 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Gli3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gli3 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Gli3 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Gli3 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Gli3 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Gli3 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Gli3 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Gli3 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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