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  3. Vectors for Human KRT81

Vectors for Human KRT81

Gene Information

  • Offical Gene Symbol KRT81
  • Species Human (Homo sapiens)
  • Offical Full Name keratin 81
  • Other Aliases HB1; Hb-1; K81; KRTHB1; MLN137; ghHkb1; hHAKB2-1
  • Other Desigations keratin, type II cuticular Hb1; hair keratin K2.9; hard keratin, type II, 1; keratin 81, type II; keratin, hair, basic, 1; metastatic lymph node 137 gene protein; type II hair keratin Hb1; type-II keratin Kb21
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. Some human genome assemblies (example T2T-CHM13) have a non-coding version of the gene due to the presence of a SNP that introduces a premature stop codon after codon 281. [provided by RefSeq, Jan 2024] Annotation information: Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
  • NCBI Gene ID 3887
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human KRT81(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KRT81 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human KRT81 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human KRT81 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human KRT81 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human KRT81 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KRT81 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human KRT81 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human KRT81 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human KRT81 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human KRT81 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human KRT81 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human KRT81 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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