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  3. Vectors for Human ABCG2

Vectors for Human ABCG2

Gene Information

  • Offical Gene Symbol ABCG2
  • Species Human (Homo sapiens)
  • Offical Full Name ATP binding cassette subfamily G member 2 (JR blood group)
  • Other Aliases ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; CDw388; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1
  • Other Desigations broad substrate specificity ATP-binding cassette transporter ABCG2; ABC transporter; ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); ATPbinding cassette transporter ABCG2; breast cancer resistance protein; broad substrate specificity ATP-binding cassette transporter ABCG2 isoform 1 (Junior blood group); mitoxantrone resistance-associated protein; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; urate exporter
  • Gene Type protein-coding
  • 개요
    The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • NCBI Gene ID 9429
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human ABCG2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCG2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human ABCG2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human ABCG2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human ABCG2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human ABCG2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCG2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human ABCG2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human ABCG2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human ABCG2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCG2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human ABCG2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human ABCG2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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