Vectors for Mouse Dkc1

Gene Information

  • Offical Gene Symbol Dkc1
  • Species Mouse (Mus musculus)
  • Offical Full Name dyskeratosis congenita 1, dyskerin
  • Other Aliases -
  • Other Desigations H/ACA ribonucleoprotein complex subunit DKC1; dyskeratosis congenita 1, dyskerin homolog; dyskerin; h/ACA ribonucleoprotein complex subunit 4; nopp140-associated protein of 57 kDa; nucleolar protein NAP57; nucleolar protein family A member 4; snoRNP protein DKC1
  • Gene Type protein-coding
  • 개요
    Predicted to enable box H/ACA snoRNA binding activity; pseudouridine synthase activity; and telomerase RNA binding activity. Predicted to contribute to telomerase activity. Acts upstream of or within ncRNA metabolic process and positive regulation of DNA biosynthetic process. Located in Cajal body and nucleolus. Is expressed in several structures, including brain; epithelium; genitourinary system; skin; and surface ectoderm. Used to study dyskeratosis congenita. Human ortholog(s) of this gene implicated in X-linked dyskeratosis congenita; aplastic anemia; and dyskeratosis congenita. Orthologous to human DKC1 (dyskerin pseudouridine synthase 1). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 245474
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Dkc1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Dkc1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Dkc1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Dkc1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Dkc1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Dkc1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Dkc1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Dkc1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Dkc1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Dkc1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Dkc1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Dkc1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Dkc1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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