Vectors for Human VPS33B

Gene Information

  • Offical Gene Symbol VPS33B
  • Species Human (Homo sapiens)
  • Offical Full Name VPS33B late endosome and lysosome associated
  • Other Aliases KDIDAR; PFIC12
  • Other Desigations vacuolar protein sorting-associated protein 33B; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33-like protein B
  • Gene Type protein-coding
  • 개요
    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  • NCBI Gene ID 26276
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human VPS33B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human VPS33B expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human VPS33B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human VPS33B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human VPS33B expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human VPS33B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human VPS33B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human VPS33B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human VPS33B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human VPS33B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human VPS33B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human VPS33B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human VPS33B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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