Vectors for Human USB1

Gene Information

  • Offical Gene Symbol USB1
  • Species Human (Homo sapiens)
  • Offical Full Name U6 snRNA biogenesis phosphodiesterase 1
  • Other Aliases C16orf57; HVSL1; Mpn1; PN; hMpn1; hUsb1
  • Other Desigations U6 snRNA phosphodiesterase 1; 3'-5' RNA exonuclease USB1; HVSL motif containing 1; U six biogenesis 1; U6 snRNA biogenesis 1; U6 snRNA phosphodiesterase; UPF0406 protein C16orf57; mutated in PN protein 1; mutated in poikiloderma with neutropenia protein 1; putative U6 snRNA phosphodiesterase
  • Gene Type protein-coding
  • 개요
    This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
  • NCBI Gene ID 79650
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human USB1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human USB1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human USB1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human USB1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human USB1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human USB1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human USB1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human USB1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human USB1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human USB1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human USB1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human USB1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human USB1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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