Vectors for Human TAP2

Gene Information

  • Offical Gene Symbol TAP2
  • Species Human (Homo sapiens)
  • Offical Full Name transporter 2, ATP binding cassette subfamily B member
  • Other Aliases ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
  • Other Desigations antigen peptide transporter 2; ABC transporter, MHC 2; ATP-binding cassette, sub-family B (MDR/TAP), member 3; peptide supply factor 2; peptide transporter PSF2; peptide transporter involved in antigen processing 2; really interesting new gene 11 protein; transporter 2, ABC (ATP binding cassette); transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
  • Gene Type protein-coding
  • 개요
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
  • NCBI Gene ID 6891
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human TAP2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAP2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human TAP2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human TAP2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human TAP2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human TAP2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAP2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human TAP2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human TAP2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human TAP2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human TAP2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human TAP2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human TAP2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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