Vectors for Human SPART

Gene Information

  • Offical Gene Symbol SPART
  • Species Human (Homo sapiens)
  • Offical Full Name spartin
  • Other Aliases SPG20; TAHCCP1
  • Other Desigations spartin; spastic paraplegia 20 (Troyer syndrome); trans-activated by hepatitis C virus core protein 1
  • Gene Type protein-coding
  • 개요
    This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
  • NCBI Gene ID 23111
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPART(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPART expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPART expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPART expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPART expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPART expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPART shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
View Vector 
Human SPART shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
View Vector 
Human SPART shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPART shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPART CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
View Vector 
Human SPART CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPART CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
View Vector 

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