Human PPP1R15B 벡터 - 렌티바이러스, AAV, shRNA & CRISPR I 벡터빌더

Gene Information

Offical Gene Symbol PPP1R15B
Species Human (Homo sapiens)
Offical Full Name protein phosphatase 1 regulatory subunit 15B
Other Aliases CREP; MSSGM2
Other Desigations protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15B
Gene Type protein-coding
개요
This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with microcephaly, short stature, and impaired glucose metabolism. [provided by RefSeq, Feb 2016]
NCBI Gene ID 84919
RefSeq Transcript
NM_032833.5
RefSeq Protein
NP_116222.4
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human PPP1R15B expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human PPP1R15B expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human PPP1R15B expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human PPP1R15B expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human PPP1R15B expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human PPP1R15B shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human PPP1R15B shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human PPP1R15B shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human PPP1R15B shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human PPP1R15B CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human PPP1R15B CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human PPP1R15B CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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