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  3. Vectors for Human PPM1F

Vectors for Human PPM1F

Gene Information

  • Offical Gene Symbol PPM1F
  • Species Human (Homo sapiens)
  • Offical Full Name protein phosphatase, Mg2+/Mn2+ dependent 1F
  • Other Aliases CAMKP; CaMKPase; FEM-2; POPX2; hFEM-2
  • Other Desigations protein phosphatase 1F; Ca(2+)/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; PP2C phosphatase; partner of PIX 2; protein fem-2 homolog; protein phosphatase 1F (PP2C domain containing)
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 9647
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human PPM1F(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1F expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human PPM1F expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human PPM1F expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human PPM1F expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human PPM1F expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1F shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human PPM1F shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human PPM1F shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human PPM1F shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PPM1F CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human PPM1F CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human PPM1F CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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