Vectors for Human POF1B

Gene Information

  • Offical Gene Symbol POF1B
  • Species Human (Homo sapiens)
  • Offical Full Name POF1B actin binding protein
  • Other Aliases POF; POF2B
  • Other Desigations protein POF1B; premature ovarian failure protein 1B; premature ovarian failure, 1B
  • Gene Type protein-coding
  • 개요
    Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene\'s expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010]
  • NCBI Gene ID 79983
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human POF1B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POF1B expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human POF1B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human POF1B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human POF1B expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human POF1B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POF1B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human POF1B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human POF1B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
View Vector 
Human POF1B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POF1B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human POF1B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
View Vector 
Human POF1B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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