Human NELFA 벡터 - 렌티바이러스, AAV, shRNA & CRISPR I 벡터빌더

Gene Information

Offical Gene Symbol NELFA
Species Human (Homo sapiens)
Offical Full Name negative elongation factor complex member A
Other Aliases NELF-A; P/OKcl.15; WHSC2
Other Desigations negative elongation factor A; wolf-Hirschhorn syndrome candidate 2 protein
Gene Type protein-coding
개요
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
NCBI Gene ID 7469
RefSeq Transcript
NM_005663.5
RefSeq Protein
NP_005654.4
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human NELFA expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human NELFA expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human NELFA expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human NELFA expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human NELFA expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human NELFA shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human NELFA shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human NELFA shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human NELFA shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human NELFA CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human NELFA CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human NELFA CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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