Vectors for Human NEDD4

Gene Information

  • Offical Gene Symbol NEDD4
  • Species Human (Homo sapiens)
  • Offical Full Name NEDD4 E3 ubiquitin protein ligase
  • Other Aliases NEDD4-1; RPF1
  • Other Desigations E3 ubiquitin-protein ligase NEDD4; HECT-type E3 ubiquitin transferase NEDD4; cell proliferation-inducing gene 53 protein; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; receptor-potentiating factor 1
  • Gene Type protein-coding
  • 개요
    This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
  • NCBI Gene ID 4734
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human NEDD4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NEDD4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human NEDD4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human NEDD4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human NEDD4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human NEDD4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NEDD4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human NEDD4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human NEDD4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human NEDD4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NEDD4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human NEDD4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human NEDD4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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