Vectors for Human GSDME

Gene Information

  • Offical Gene Symbol GSDME
  • Species Human (Homo sapiens)
  • Offical Full Name gasdermin E
  • Other Aliases DFNA5; ICERE-1
  • Other Desigations gasdermin-E; DFNA5, deafness associated tumor suppressor; inversely correlated with estrogen receptor expression 1; non-syndromic hearing impairment protein 5; nonsyndromic hearing impairment protein
  • Gene Type protein-coding
  • 개요
    Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1687
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human GSDME(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GSDME expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human GSDME expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human GSDME expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human GSDME expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human GSDME expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GSDME shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human GSDME shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human GSDME shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human GSDME shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GSDME CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human GSDME CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human GSDME CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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  • 바이러스 패키징
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  • RNA preparation
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