Vectors for Human FUT3

Gene Information

  • Offical Gene Symbol FUT3
  • Species Human (Homo sapiens)
  • Offical Full Name fucosyltransferase 3 (Lewis blood group)
  • Other Aliases CD174; FT3B; FucT-III; LE; Les
  • Other Desigations 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3; 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase 3; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; Lewis FT; alpha-(1,3/1,4)-fucosyltransferase; alpha-3-fucosyltransferase FUT3; blood group Lewis alpha-4-fucosyltransferase; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); fucosyltransferase III; galactoside 3(4)-L-fucosyltransferase
  • Gene Type protein-coding
  • 개요
    The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Differences in the expression of this gene are associated with host susceptibility to viral infection. [provided by RefSeq, Aug 2020] Annotation information: Annotation category: suggests misassembly
  • NCBI Gene ID 2525
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human FUT3(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FUT3 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human FUT3 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human FUT3 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human FUT3 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human FUT3 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FUT3 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human FUT3 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human FUT3 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human FUT3 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FUT3 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human FUT3 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human FUT3 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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