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  3. Vectors for Human DYRK1A

Vectors for Human DYRK1A

Gene Information

  • Offical Gene Symbol DYRK1A
  • Species Human (Homo sapiens)
  • Offical Full Name dual specificity tyrosine phosphorylation regulated kinase 1A
  • Other Aliases DYRK; DYRK1; HP86; MNB; MNBH; MRD7
  • Other Desigations dual specificity tyrosine-phosphorylation-regulated kinase 1A; MNB/DYRK protein kinase; dual specificity YAK1-related kinase; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; mnb protein kinase homolog hp86; protein kinase minibrain homolog; serine/threonine kinase MNB; serine/threonine-specific protein kinase
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5\' UTR or in the 3\' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1859
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human DYRK1A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYRK1A expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human DYRK1A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human DYRK1A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human DYRK1A expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human DYRK1A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYRK1A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human DYRK1A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human DYRK1A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human DYRK1A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DYRK1A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human DYRK1A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human DYRK1A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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