Vectors for Human DNASE2

Gene Information

  • Offical Gene Symbol DNASE2
  • Species Human (Homo sapiens)
  • Offical Full Name deoxyribonuclease 2, lysosomal
  • Other Aliases AIPCS; DNASE2A; DNL; DNL2
  • Other Desigations deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; R31240_2; acid DNase; deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; lysosomal DNase II
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1777
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DNASE2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DNASE2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DNASE2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DNASE2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DNASE2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DNASE2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DNASE2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human DNASE2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human DNASE2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human DNASE2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DNASE2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human DNASE2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DNASE2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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