Vectors for Human CCDC88C

Gene Information

  • Offical Gene Symbol CCDC88C
  • Species Human (Homo sapiens)
  • Offical Full Name coiled-coil domain containing 88C
  • Other Aliases DAPLE; HKRP2; HYC1; KIAA1509; SCA40
  • Other Desigations protein Daple; Dvl-associating protein with a high frequency of leucine residues; hook-related protein 2; spinocerebellar ataxia 40
  • Gene Type protein-coding
  • 개요
    This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]
  • NCBI Gene ID 440193
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CCDC88C(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CCDC88C expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CCDC88C expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CCDC88C expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CCDC88C expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CCDC88C expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CCDC88C shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CCDC88C shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CCDC88C shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CCDC88C shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CCDC88C CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CCDC88C CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CCDC88C CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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