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  3. Vectors for Human BMPR2

Vectors for Human BMPR2

Gene Information

  • Offical Gene Symbol BMPR2
  • Species Human (Homo sapiens)
  • Offical Full Name bone morphogenetic protein receptor type 2
  • Other Aliases BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
  • Other Desigations bone morphogenetic protein receptor type-2; BMP type II receptor; BMP type-2 receptor; bone morphogenetic protein receptor type II; bone morphogenetic protein receptor, type II (serine/threonine kinase); type II activin receptor-like kinase; type II receptor for bone morphogenetic protein-4
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]
  • NCBI Gene ID 659
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human BMPR2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BMPR2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human BMPR2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human BMPR2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human BMPR2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human BMPR2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BMPR2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human BMPR2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human BMPR2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human BMPR2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BMPR2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human BMPR2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human BMPR2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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