Human BCCIP 벡터 - 렌티바이러스, AAV, shRNA & CRISPR I 벡터빌더

Gene Information

Offical Gene Symbol BCCIP
Species Human (Homo sapiens)
Offical Full Name BRCA2 and CDKN1A interacting protein
Other Aliases TOK-1; TOK1
Other Desigations BRCA2 and CDKN1A-interacting protein; BCCIPalpha; BCCIPbeta; BRCA2 and Cip1/p21 interacting protein; TOK-1alpha; TOK-1beta; cdk inhibitor p21 binding protein; p21- and CDK-associated protein 1; protein TOK-1
Gene Type protein-coding
개요
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
NCBI Gene ID 56647
RefSeq Transcript
NM_016567.4; NM_078468.3; NM_078469.3
RefSeq Protein
NP_057651.1; NP_510868.1; NP_510869.1
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human BCCIP expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human BCCIP expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human BCCIP expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human BCCIP expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human BCCIP expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human BCCIP shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human BCCIP shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human BCCIP shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human BCCIP shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human BCCIP CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human BCCIP CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human BCCIP CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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