Vectors for Human BCAR4

Gene Information

Offical Gene Symbol BCAR4
Species Human (Homo sapiens)
Offical Full Name breast cancer anti-estrogen resistance 4
Other Aliases -
Other Desigations breast cancer anti-estrogen resistance 4 (non-protein coding); breast cancer antiestrogen resistance 4 protein
Gene Type ncRNA
개요
This gene produces a spliced long non-coding RNA (lncRNA) that has been implicated in breast cancer metastasis. It was originally identified in a screen for genes responsible for the development of resistance to anti-estrogens in breast cancer cells. It is thought that release of CCL21 enables this lncRNA to bind to the SNIP1 and PNUTS transcription factors, thereby activating a non-canonical GLI-dependent hedgehog signaling pathway that promotes cancer cell migration and invasion. A similar gene in cow expresses a protein in mature oocytes and preimplantation embryos. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2015]
NCBI Gene ID 400500
RefSeq Transcript
NR_024049.1; NR_024050.1; NR_131216.1; NR_131217.1; NR_131222.1
RefSeq Protein
-; -; -; -; -
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

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