Vectors for Zebrafish selenop

Gene Information

  • Offical Gene Symbol selenop
  • Species Zebrafish (Danio rerio)
  • Offical Full Name selenoprotein P
  • Other Aliases SePPa; SelPa; cb688; sepp1a; wu:fa55a04; wu:fb38a09; wu:fj79f04
  • Other Desigations selenoprotein Pa; selenoprotein P, 1a; selenoprotein P, plasma, 1a; zSelPa
  • Gene Type protein-coding
  • 개요
    This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma in mammals. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (17 in zebrafish), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3\' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. A paralog of this gene exists on chromosome 2 (GeneID:791479). [provided by RefSeq, Aug 2017]
  • NCBI Gene ID 352931
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Zebrafish selenop(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Zebrafish selenop expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Zebrafish selenop expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Zebrafish selenop expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Zebrafish selenop expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Zebrafish selenop expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189

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