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  3. Vectors for Human SHC1

Vectors for Human SHC1

Gene Information

  • Offical Gene Symbol SHC1
  • Species Human (Homo sapiens)
  • Offical Full Name SHC adaptor protein 1
  • Other Aliases SHC; SHCA
  • Other Desigations SHC-transforming protein 1; SH2 domain protein C1; SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A
  • Gene Type protein-coding
  • 개요
    This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
  • NCBI Gene ID 6464
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human SHC1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SHC1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human SHC1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human SHC1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human SHC1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human SHC1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SHC1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human SHC1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human SHC1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human SHC1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SHC1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human SHC1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human SHC1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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  • 바이러스 패키징
  • CRISPR targeting
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  • Library construction
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  • RNA preparation
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  • and more...