Vectors for Human SF3B2

Gene Information

  • Offical Gene Symbol SF3B2
  • Species Human (Homo sapiens)
  • Offical Full Name splicing factor 3b subunit 2
  • Other Aliases CFM; Cus1; HFM; SAP145; SF3B145; SF3b1; SF3b150
  • Other Desigations splicing factor 3B subunit 2; SAP 145; pre-mRNA splicing factor SF3b 145 kDa subunit; spliceosome associated protein 145; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
  • Gene Type protein-coding
  • 개요
    This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron\'s branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 10992
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SF3B2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SF3B2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human SF3B2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human SF3B2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human SF3B2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human SF3B2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SF3B2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human SF3B2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human SF3B2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human SF3B2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SF3B2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human SF3B2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human SF3B2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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