Vectors for Human RNF34

Gene Information

  • Offical Gene Symbol RNF34
  • Species Human (Homo sapiens)
  • Offical Full Name ring finger protein 34
  • Other Aliases CARP-1; CARP1; RFI; RIF; RIFF; hRFI
  • Other Desigations E3 ubiquitin-protein ligase RNF34; FYVE-RING finger protein MOMO; RING finger protein RIFF; RING-type E3 ubiquitin transferase RNF34; caspase regulator CARP1; caspases-8 and -10-associated RING finger protein 1; human RING finger homologous to inhibitor of apoptosis protein; ring finger protein 34, E3 ubiquitin protein ligase
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
  • NCBI Gene ID 80196
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RNF34(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF34 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RNF34 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RNF34 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RNF34 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RNF34 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF34 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RNF34 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RNF34 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RNF34 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RNF34 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RNF34 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RNF34 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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