Vectors for Human RFXANK

Gene Information

  • Offical Gene Symbol RFXANK
  • Species Human (Homo sapiens)
  • Offical Full Name regulatory factor X associated ankyrin containing protein
  • Other Aliases ANKRA1; BLS; F14150_1; RFX-B
  • Other Desigations DNA-binding protein RFXANK; RFX-Bdelta4; ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; regulatory factor X subunit B
  • Gene Type protein-coding
  • 개요
    Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
  • NCBI Gene ID 8625
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human RFXANK(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RFXANK expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human RFXANK expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human RFXANK expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human RFXANK expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human RFXANK expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RFXANK shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human RFXANK shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human RFXANK shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human RFXANK shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human RFXANK CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human RFXANK CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human RFXANK CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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