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  3. Vectors for Human ITM2B

Vectors for Human ITM2B

Gene Information

  • Offical Gene Symbol ITM2B
  • Species Human (Homo sapiens)
  • Offical Full Name integral membrane protein 2B
  • Other Aliases ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; RDGCA; imBRI2
  • Other Desigations integral membrane protein 2B; ABri/ADan amyloid peptide; BRICHOS domain containing 2B; epididymis secretory sperm binding protein; immature BRI2; transmembrane protein BRI
  • Gene Type protein-coding
  • 개요
    Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
  • NCBI Gene ID 9445
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human ITM2B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITM2B expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human ITM2B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human ITM2B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human ITM2B expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human ITM2B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITM2B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human ITM2B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human ITM2B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human ITM2B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ITM2B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human ITM2B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human ITM2B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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