Vectors for Human IPO5

Gene Information

  • Offical Gene Symbol IPO5
  • Species Human (Homo sapiens)
  • Offical Full Name importin 5
  • Other Aliases IMB3; KPNB3; Pse1; RANBP5; imp5
  • Other Desigations importin-5; Kap beta3 import receptor; PSE1 homolog; RAN binding protein 5; Ran_GTP binding protein 5; importin beta-3 subunit; importin subunit beta-3; karyopherin (importin) beta 3; karyopherin beta-3; ran-binding protein 5
  • Gene Type protein-coding
  • 개요
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 3843
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human IPO5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IPO5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human IPO5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human IPO5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human IPO5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human IPO5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IPO5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human IPO5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human IPO5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human IPO5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human IPO5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human IPO5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human IPO5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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