Vectors for Human HYAL2

Gene Information

  • Offical Gene Symbol HYAL2
  • Species Human (Homo sapiens)
  • Offical Full Name hyaluronidase 2
  • Other Aliases LUCA2
  • Other Desigations hyaluronidase-2; PH-20 homolog; PH20 homolog; hyal-2; hyaluronoglucosaminidase 2; lung carcinoma protein 2; lysosomal hyaluronidase
  • Gene Type protein-coding
  • 개요
    This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5\' UTR.[provided by RefSeq, Mar 2010]
  • NCBI Gene ID 8692
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HYAL2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HYAL2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HYAL2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HYAL2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HYAL2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HYAL2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HYAL2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human HYAL2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HYAL2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HYAL2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HYAL2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human HYAL2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HYAL2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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