Vectors for Human HSPB8

Gene Information

  • Offical Gene Symbol HSPB8
  • Species Human (Homo sapiens)
  • Offical Full Name heat shock protein family B (small) member 8
  • Other Aliases CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HMND2; HSP22; HSPB8-N1; HSPB8-N2
  • Other Desigations heat shock protein beta-8; E2-induced gene 1 protein; alpha-crystallin C chain; heat shock 22kDa protein 8; heat shock 27kDa protein 8; protein kinase H11; small stress protein-like protein HSP22
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 26353
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HSPB8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HSPB8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HSPB8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HSPB8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HSPB8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human HSPB8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HSPB8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HSPB8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human HSPB8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HSPB8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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