Vectors for Human HSPB1

Gene Information

  • Offical Gene Symbol HSPB1
  • Species Human (Homo sapiens)
  • Offical Full Name heat shock protein family B (small) member 1
  • Other Aliases CMT2F; HEL-S-102; HMN2B; HMND3; HS.76067; HSP27; HSP28; Hsp25; SRP27
  • Other Desigations heat shock protein beta-1; 28 kDa heat shock protein; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; stress-responsive protein 27
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
  • NCBI Gene ID 3315
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HSPB1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HSPB1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HSPB1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HSPB1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HSPB1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human HSPB1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HSPB1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HSPB1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSPB1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human HSPB1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HSPB1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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