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  3. Vectors for Human HSD17B8

Vectors for Human HSD17B8

Gene Information

  • Offical Gene Symbol HSD17B8
  • Species Human (Homo sapiens)
  • Offical Full Name hydroxysteroid 17-beta dehydrogenase 8
  • Other Aliases D6S2245E; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1; dJ1033B10.9
  • Other Desigations (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-HSD 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; KAR alpha subunit; estradiol 17-beta-dehydrogenase 8; estrogen 17-oxidoreductase; ke-6; protein Ke6; really interesting new gene 2 protein; short chain dehydrogenase/reductase family 30C member 1; testosterone 17-beta-dehydrogenase 8
  • Gene Type protein-coding
  • 개요
    In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 7923
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human HSD17B8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSD17B8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human HSD17B8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human HSD17B8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human HSD17B8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human HSD17B8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSD17B8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human HSD17B8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human HSD17B8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human HSD17B8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HSD17B8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human HSD17B8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human HSD17B8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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