Human HLA-F 벡터 - 렌티바이러스, AAV, shRNA & CRISPR I 벡터빌더

Gene Information

Offical Gene Symbol HLA-F
Species Human (Homo sapiens)
Offical Full Name major histocompatibility complex, class I, F
Other Aliases CDA12; HLA-5.4; HLA-CDA12; HLAF
Other Desigations HLA class I histocompatibility antigen, alpha chain F; HLA F antigen; MHC class I antigen F; leukocyte antigen F; non-classical MHC class I antigen; nonclassical MHC class I antigen
Gene Type protein-coding
개요
This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
NCBI Gene ID 3134
RefSeq Transcript
NM_001098478.2; NM_001098479.2; NM_018950.3
RefSeq Protein
NP_001091948.1; NP_001091949.1; NP_061823.2
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human HLA-F expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human HLA-F expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human HLA-F expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human HLA-F expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human HLA-F expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human HLA-F shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human HLA-F shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human HLA-F shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human HLA-F shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human HLA-F CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human HLA-F CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human HLA-F CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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