Vectors for Human GPT

Gene Information

  • Offical Gene Symbol GPT
  • Species Human (Homo sapiens)
  • Offical Full Name glutamic--pyruvic transaminase
  • Other Aliases AAT1; ALT; ALT1; GPT1; SGPT
  • Other Desigations alanine aminotransferase 1; alanine aminotransferase; alanine transaminase; glutamate pyruvate transaminase 1; glutamic--pyruvic transaminase 1; glutamic-alanine transaminase 1; glutamic-pyruvate transaminase (alanine aminotransferase)
  • Gene Type protein-coding
  • 개요
    This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009] Annotation information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for disease process.
  • NCBI Gene ID 2875
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human GPT(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GPT expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human GPT expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human GPT expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human GPT expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human GPT expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GPT shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human GPT shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human GPT shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human GPT shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GPT CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human GPT CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human GPT CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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