Vectors for Human CEP290

Gene Information

  • Offical Gene Symbol CEP290
  • Species Human (Homo sapiens)
  • Offical Full Name centrosomal protein 290
  • Other Aliases 3H11Ag; BBS14; CT87; JBTS5; LCA10; MKS4; NPHP6; POC3; SLSN6; rd16
  • Other Desigations centrosomal protein of 290 kDa; Bardet-Biedl syndrome 14 protein; CTCL tumor antigen se2-2; Meckel syndrome, type 4; POC3 centriolar protein homolog; cancer/testis antigen 87; centrosomal protein 290kDa; monoclonal antibody 3H11 antigen; nephrocytsin-6; prostate cancer antigen T21; tumor antigen se2-2
  • Gene Type protein-coding
  • 개요
    This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 80184
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CEP290(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEP290 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CEP290 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CEP290 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CEP290 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CEP290 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEP290 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CEP290 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CEP290 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CEP290 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CEP290 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CEP290 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CEP290 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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