Vectors for Human CDKN1C

Gene Information

  • Offical Gene Symbol CDKN1C
  • Species Human (Homo sapiens)
  • Offical Full Name cyclin dependent kinase inhibitor 1C
  • Other Aliases BWCR; BWS; KIP2; WBS; p57; p57Kip2
  • Other Desigations cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57
  • Gene Type protein-coding
  • 개요
    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  • NCBI Gene ID 1028
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CDKN1C(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDKN1C expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CDKN1C expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CDKN1C expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CDKN1C expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CDKN1C expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDKN1C shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CDKN1C shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CDKN1C shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CDKN1C shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDKN1C CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CDKN1C CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CDKN1C CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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