Vectors for Human SPINK5

Gene Information

  • Offical Gene Symbol SPINK5
  • Species Human (Homo sapiens)
  • Offical Full Name serine peptidase inhibitor Kazal type 5
  • Other Aliases LEKTI; LETKI; NETS; NS; VAKTI
  • Other Desigations serine protease inhibitor Kazal-type 5; lympho-epithelial Kazal-type-related inhibitor; lymphoepithelial Kazal-type-related inhibitor
  • Gene Type protein-coding
  • 개요
    This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
  • NCBI Gene ID 11005
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPINK5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPINK5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPINK5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPINK5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPINK5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPINK5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPINK5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SPINK5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SPINK5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPINK5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPINK5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SPINK5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPINK5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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