Vectors for Human SPG21

Gene Information

  • Offical Gene Symbol SPG21
  • Species Human (Homo sapiens)
  • Offical Full Name SPG21 abhydrolase domain containing, maspardin
  • Other Aliases ABHD21; ACP33; BM-019; GL010; MAST
  • Other Desigations maspardin; SPG21, maspardin; acid cluster protein 33; spastic paraplegia 21 (autosomal recessive, Mast syndrome)
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
  • NCBI Gene ID 51324
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPG21(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPG21 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPG21 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPG21 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPG21 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPG21 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPG21 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SPG21 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SPG21 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPG21 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPG21 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SPG21 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPG21 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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