Vectors for Human SPATA18

Gene Information

  • Offical Gene Symbol SPATA18
  • Species Human (Homo sapiens)
  • Offical Full Name spermatogenesis associated 18
  • Other Aliases Mieap; SPETEX1
  • Other Desigations mitochondria-eating protein; spermatogenesis associated 18 homolog; testis tissue sperm-binding protein Li 71n
  • Gene Type protein-coding
  • 개요
    This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
  • NCBI Gene ID 132671
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPATA18(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPATA18 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPATA18 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPATA18 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPATA18 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPATA18 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPATA18 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SPATA18 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SPATA18 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPATA18 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPATA18 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SPATA18 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPATA18 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
View Vector 

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