Vectors for Human SPAG6

Gene Information

  • Offical Gene Symbol SPAG6
  • Species Human (Homo sapiens)
  • Offical Full Name sperm associated antigen 6
  • Other Aliases CFAP194; CT141; FAP194; Repro-SA-1; pf16
  • Other Desigations sperm-associated antigen 6; axoneme central apparatus protein; protein PF16 homolog; sperm flagellar protein; testicular tissue protein Li 176
  • Gene Type protein-coding
  • 개요
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  • NCBI Gene ID 9576
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPAG6(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPAG6 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPAG6 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPAG6 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPAG6 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPAG6 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPAG6 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SPAG6 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SPAG6 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPAG6 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPAG6 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SPAG6 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPAG6 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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