Vectors for Human SPACA1

Gene Information

  • Offical Gene Symbol SPACA1
  • Species Human (Homo sapiens)
  • Offical Full Name sperm acrosome associated 1
  • Other Aliases SAMP32
  • Other Desigations sperm acrosome membrane-associated protein 1; sperm acrosomal membrane-associated protein 32
  • Gene Type protein-coding
  • 개요
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 81833
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SPACA1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPACA1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SPACA1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SPACA1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SPACA1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SPACA1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPACA1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SPACA1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SPACA1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SPACA1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SPACA1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SPACA1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SPACA1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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